With vast
amounts of information being generated due to advancements in biotechnology,
there arises a need to effectively control and manage the information so
generated. Information Technology provides a mechanism more popularly known as
bioinformatics, which facilitates this process. Information technology has
become a critical factor in pharmaceutical research and development .Bioinformatics
is the computer assisted data management discipline that helps us gather,
analyze, and represent information in order to educate ourselves, understand
life’s processes in the healthy and disease states, and find new or better
drugs. This field has exploded out of the world of molecular biology and the
Human Genome Project. Pharmaceutical companies are achieving increased research
efficiency by the introduction of new approaches to the design, synthesis,
screening and optimization of drug candidates. IT is an important support
function for all of those activities and there are certain functions and
operations that cannot be performed without IT. Informatics represents the
deployment of Information Technology to manage, analyze, and store biological
data. Beyond data management, informatics represents the only way to analyze
large pools of genomic information. Informatics finds application in Target
Validation, Lead Optimization, Exploratory development etc.
Bioinformatics
plays a key role in functionalities such as gather, store, classify, analyze,
and distribute biological information derived from sequencing and functional
analysis projects. In Bioinformatics, the real long-term value lies in
converting the data into useful therapeutics and hence efforts are on to make
the bioinformatics tools as standardized and easy as possible, which is similar
to the development of standardized computer operating systems. Most publicly
held informatics companies had initial public offerings in the second half of
2000. Since then, the biotechnology index has suffered a major setback, and
informatics stocks have reacted in sympathy mostly to the downside. Growth in
the informatics industry is largely contingent on continued spending on drug
discovery. The market for Bioinformatics isn’t large enough to support a
company built around one or two high-cost software programs targeted to a
relatively small user group. As we assess the market or potential market of
Bioinformatics we must consider the strategies effective to reach different, or
all, parts of the potential market. Strategies focused at the high margin big
Pharma market (limited in opportunities) or strategies designed to embrace all
biological scientist (but of reduced or variable margin). Also, certain
bioinformatics-based companies are leveraging their technologies to become fully
integrated drug discovery operations. Other bioinformatics companies are
merging with drug discovery companies, resulting in a substitute technological
approach to drug development.
The
convergence of biotechnology and computing has already resulted in a number of
alliances, which could result in mergers between previously distinct
industries. In future, we may see a combination of pharmaceutical and computing
firms bringing together their research as well as IT capabilities. In future we
may see alliances between pharmaceutical, software as well as firms, which have
strong marketing capabilities. The field would also witness the entry of new
players such as computing and telecommunication firms. The challenge facing
bioinformatics researchers is simply making sense of the plethora of genomic
data while constantly refining their technology, research approaches. The real
opportunities are in finding out how all the shards of information relate to
one another, and what this means for real world applications. Recognizing
bioinformatics as central to accelerating drug discovery, big pharma and
biotech firms are expected to invest heavily in internal capabilities, or meet
their needs through outsourcing. As the market matures, collaborative industry
initiatives may drive even more bioinformatics demand. Innovation will depend
on the integration of databases across functions and across companies.
Ritu
Pal
Marketing
Executive
Excellent blog having great focus on bioinformatics..The science of Bioinformatics,which is the melding of molecular biology with computer science, is essential to the use of genomic information in understanding human diseases and in the identification of new molecular targets for drug discovery.
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